ultrafiltration centrifuge tube
An ultrafiltration centrifuge tube is a sophisticated laboratory device designed for efficient molecular separation and concentration of biological samples. These specialized tubes incorporate a semipermeable membrane with specific molecular weight cut-offs, allowing for precise separation of proteins, nucleic acids, and other biomolecules. The tube consists of two main compartments separated by the ultrafiltration membrane, enabling the retention of larger molecules while smaller molecules and solvents pass through during centrifugation. The design typically features a vertical membrane configuration that minimizes protein concentration polarization and maintains high recovery rates. Modern ultrafiltration centrifuge tubes are manufactured using high-grade materials that ensure chemical compatibility with common laboratory reagents and provide excellent sample recovery. They are available in various sizes and molecular weight cut-off ranges, making them versatile tools for multiple applications including protein concentration, buffer exchange, protein purification, and sample preparation for downstream analysis. The tubes are engineered to withstand high centrifugal forces while maintaining membrane integrity and preventing sample loss.